How much alcohol a person drinks, genetic factors, gender, body mass, and general state of health all influence how a person’s health responds to chronic heavy drinking.

Liver disease Alcohol is mostly metabolized in the liver, which is why the liver is particularly at risk of damage. The body metabolizes alcohol into acetaldehyde, a substance thatTrusted Source is both toxic and carcinogenic.

Pancreatitis Overconsumption of alcohol can lead to pancreatitis, a painful inflammation of the pancreas that often requires hospitalization.

Cancer Chronic alcohol use increases danger. Mouth, oesophagus, larynx, stomach, liver, colon, rectum, and breast cancers. Acetaldehyde and alcohol increase danger.

Ulcers and gastrointestinal problems Heavy drinking can cause problemsTrusted Source with the digestive system, such as stomach ulcers, acid reflux, heartburn, and inflammation of the stomach lining, known as gastritis.

Immune system dysfunction Drinking too much weakens the immune system, making the body vulnerable to infectious diseases, such as pneumonia and tuberculosis.

Brain damage Alcohol causes blurred vision, memory lapses, slurred speech, walking difficulties, and decreased reaction time. All are brain effects.

Drinking alcohol in any amount is linked to car crashes, domestic violence, falls, drowning, occupational injuries, suicide, and homicide.